diff --git a/pyrogram/filters.py b/pyrogram/filters.py
index 8b00fe81..3c3bc650 100644
--- a/pyrogram/filters.py
+++ b/pyrogram/filters.py
@@ -890,7 +890,12 @@ def command(commands: Union[str, List[str]], prefixes: Union[str, List[str]] = "
     command_re = re.compile(r"([\"'])(.*?)(?<!\\)\1|(\S+)")
 
     async def func(flt, client: pyrogram.Client, message: Message):
+        usernames = []
         username = client.me.username or ""
+        if client.me.usernames:
+            usernames.append(username)
+            for user in client.me.usernames:
+                usernames.append(user.username)
         text = message.text or message.caption
         message.command = None
 
@@ -904,6 +909,24 @@ def command(commands: Union[str, List[str]], prefixes: Union[str, List[str]] = "
             without_prefix = text[len(prefix):]
 
             for cmd in flt.commands:
+                if usernames:
+                    for username in usernames:
+                        if not re.match(rf"^(?:{cmd}(?:@?{username})?)(?:\s|$)", without_prefix,
+                                        flags=re.IGNORECASE if not flt.case_sensitive else 0):
+                            continue
+
+                        without_command = re.sub(rf"{cmd}(?:@?{username})?\s?", "", without_prefix, count=1,
+                                                flags=re.IGNORECASE if not flt.case_sensitive else 0)
+
+                        # match.groups are 1-indexed, group(1) is the quote, group(2) is the text
+                        # between the quotes, group(3) is unquoted, whitespace-split text
+
+                        # Remove the escape character from the arguments
+                        message.command = [cmd] + [
+                            re.sub(r"\\([\"'])", r"\1", m.group(2) or m.group(3) or "")
+                            for m in command_re.finditer(without_command)
+                        ]
+                        return True
                 if not re.match(rf"^(?:{cmd}(?:@?{username})?)(?:\s|$)", without_prefix,
                                 flags=re.IGNORECASE if not flt.case_sensitive else 0):
                     continue
@@ -1011,12 +1034,22 @@ class user(Filter, set):
         )
 
     async def __call__(self, _, message: Message):
+        is_usernames_in_filters = False
+        if message.from_user.usernames:
+            for username in message.from_user.usernames:
+                if (
+                    username.username in self
+                    or username.username.lower() in self
+                ):
+                    is_usernames_in_filters = True
+                    break
         return (message.from_user
                 and (message.from_user.id in self
                      or (message.from_user.username
                          and message.from_user.username.lower() in self)
                      or ("me" in self
-                         and message.from_user.is_self)))
+                         and message.from_user.is_self))
+                    or is_usernames_in_filters)
 
 
 # noinspection PyPep8Naming
@@ -1044,6 +1077,15 @@ class chat(Filter, set):
 
     async def __call__(self, _, message: Union[Message, Story]):
         if isinstance(message, Story):
+            is_usernames_in_filters = False
+            if message.sender_chat.usernames:
+                for username in message.sender_chat.usernames:
+                    if (
+                        username.username in self
+                        or username.username.lower() in self
+                    ):
+                        is_usernames_in_filters = True
+                        break
             return (
                     message.sender_chat
                     and (
@@ -1062,8 +1104,17 @@ class chat(Filter, set):
                             and message.from_user.username.lower() in self
                         )
                     )
-                )
+                ) or is_usernames_in_filters
         else:
+            is_usernames_in_filters = False
+            if message.chat.usernames:
+                for username in message._chat.usernames:
+                    if (
+                        username.username in self
+                        or username.username.lower() in self
+                    ):
+                        is_usernames_in_filters = True
+                        break
             return (message.chat
                     and (message.chat.id in self
                          or (message.chat.username
@@ -1071,7 +1122,10 @@ class chat(Filter, set):
                          or ("me" in self
                              and message.from_user
                              and message.from_user.is_self
-                             and not message.outgoing)))
+                             and not message.outgoing))
+                         or (is_usernames_in_filters
+                            and not message.outgoing)
+            )
 
 
 # noinspection PyPep8Naming